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A Pocket Guide to Adult HIV/AIDS Treatment
February 2006 edition |
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Step 1: Screen Patients for Risk Behaviors
TOP
- Behaviors and clinical factors associated with HIV, other STDs, and
IV drug use (every visit)
- STD symptoms: most are asymptomatic (every visit)
- Pregnancy
- Screening tests
Routine
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- Syphilis serology: RPR or VDRL*
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- Trichomonas wet mount or culture
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- All women
25 years and sexually active
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- Cervical specimen for C. trachomatis
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- All men and women not included above
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- Screening for GC and C. trachomatis by urethral (men) or cervical (women) specimen or first catch urine for NAAT*
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- Anal swab for GC culture and, if available, for C. trachomatis
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- Pharyngeal culture for GC
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* Repeat RPR or VDRL annually. Consider repeating screening tests for N. gonorrhea and C. trachomatis annually or more frequently if sexually active, if screening previous test positive, or other high risk
Step 2: Behavioral Interventions
TOP
- Prevention messages should be provided with each visit
- Communicate factors that influence transmission and risk reduction; i.e. abstinence, sex with condoms, sex exclusively with HIV-infected person(s). If sex with persons with unknown or negative serologic status, stress proper condom use.
- IDU
- Stop using drugs
- Enter substance abuse treatment
- If patient continues to use drugs:
- Never reuse or share needles, water, or drug preparation
equipment
- Use only syringes from reliable sources (pharmacies)
- Use new syringe; if not possible-boil or disinfect with bleach
(http://www.cdcnpin.org)
- Use sterile water to prepare drugs; otherwise use tap water
- Use new or disinfected cooker and new cotton
- Clean injection site with new alcohol swab
- Safely dispose of needle
- Per act relative risks of HIV transmission
- Condom vs no condom: 1:20
- Compared to insertive vaginal sex: receptive vaginal sex 2:1,
receptive anal sex 10:1, insertive fellatio 1:10, insertive anal sex
1.3:1, receptive fellatio 1:5 (STD 2002;29:38)
Note: Risks for condom use and acts are multiplicative; e.g, for
the ratio for anal sex without a condom vs vaginal insertive sex
with a condom is 100:1
- Viral load: each log10 reduction in viral load reduces probability of transmission 2.5 fold
- Non-occupational postexposure prophylaxis: not endorsed by CDC due to “uncertain effectiveness”
- HAART recipients: decreases in VL probably reduces but risk transgression in behavior eliminates this benefit; with structured treatment interruption, warn patient that viral load increases as does risk of transmission
Step 3: Partner Counseling and Notification TOP
- Laws: Follow local and state laws for reporting sex and needlesharing partners
- Initial Visit: Ask if all sex and needlesharing partners have been notified
- Follow-ups: Ask about new sex or needlesharing partners who have not been notified
- Referrals: All contacts should be referred to the Health Department; arrange for notification and testing without identifying source; patients who elect not to notify partners should be referred to the Health Department to conduct these activities
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