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The HIV/AIDS Program: HAB Performance Measures Group 3

 

Hepatitis B Screening

 

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Performance Measure
 
Numerator
 
Denominator
 
Patient Exclusions
 
Data Element
 
Data Sources
 
National Goals, Targets or Benchmarks for Comparison
 
Outcome Measures for Consideration
 
Basis for Selection and Placement in Group 2
 
US Public Health Service Guidelines
 
References/Notes
 
Performance Measure: Hepatits B Screening - OPR-Related Measure: Yes  

Percentage of clients [ 1 ] with HIV infection who have been screened for Hepatitis B virus infection status.

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Numerator  

Number of HIV-infected clients who have documented Hepatitis B infection status [ 2 ] in the health record

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Denominator  

Number of HIV-infected clients who had a medical visit with a provider with prescribing privileges [ 3 ] at least once in the measurement year

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Patient Exclusions  

Patients with documentation of complete Hepatitis B vaccination.

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Data Elements  
  1. Is the client HIV-infected? (Y/N)
    1. If yes, is there documentation of Hepatitis B infection status in the health record? (Y/N)
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Data Sources  
  • Electronic Medical Record/Electronic Health Record
  • CAREWare, Lab Tracker or other electronic data base
  • Medical record data abstraction by grantee of a sample of records
  • Billing records
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National Goals, Targets, or Benchmarks for Comparison 

None available at this time

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Outcome Measures for Consideration 

Hepatitis-related mortality rates in the clinic population

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Basis for Selection and Placement in Group 3 

Hepatitis B virus (HBV) is the leading cause of chronic liver disease worldwide. In developed countries, HBV is transmitted primarily through sexual contact and injection drug use. Even though risk factors are similar, HBV is transmitted more efficiently than HIV-1. Up to 90% of HIV-1-infected persons have at least one serum marker of previous exposure to HBV, and approximately 10% have chronic Hepatitis B, as evidenced by the detection of hepatitis B surface antigen (HBsAg) in the serum persisting for a minimum of 6 months. [ 4 ]  

It is not clear that treatment of hepatitis B virus (HBV) improves the course of HIV, nor is there evidence that treatment of HIV alters the course of HBV. However, several liver-associated complications that are ascribed to flares in HBV activity or toxicity of antiretroviral agents can affect the treatment of HIV in patients with HBV coinfection. [ 5 ] Therefore, providers should know the HBV status of all patients with HIV. This also will guide the choice of medications for HIV treatment in the context of any possible HBV treatment. For patients who are HBV negative, prophylaxis is recommended. [ 6 ]

The measure is placed in Group 3 because it focuses on similar aspects of care (HBV and HCV) previously captured in measures included in Group 2.

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US Public Health Service Guidelines 

"All HIV-infected persons should be tested for HBV infection. Initial testing should be performed because these will identify the majority of patients with chronic hepatitis B or who need vaccination to prevent infection." [ 7 ]

"It is not clear that treatment of hepatitis B virus (HBV) improves the course of HIV, nor is there evidence that treatment of HIV alters the course of HBV. However, s everal liver-associated complications that are ascribed to flares in HBV activity or toxicity of antiretroviral agents can affect the treatment of HIV in patients with HBV coinfection." [ 8 ]

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References/Notes 

[1] "Clients" includes all clients aged 13 years or older.

[2] Markers of Hepatitis B infection include Hep B Surface Antigen, Hep B e Antigen, Hep B e Antibody or Hep B DNA.

[3] A "provider with prescribing privileges" is a health care professional who is certified in their jurisdiction to prescribe medications.

[4] Centers for Disease Control and Prevention. Guidelines for Prevention and Treatment of Opportunistic Infections in HIV-Infected Adults and Adolescents. June 18, 2008; 1-134. (http://aidsinfo.nih.gov/contentfiles/Adult_OI.pdf )

[5] Panel on Antiretroviral Guidelines for Adult and Adolescents. Guidelines for the Use of Antiretroviral Agents in HIV-1-Infected Adults and Adolescents. Department of Health and Human Services. January 29, 2008; 1-128. (http://aidsinfo.nih.gov/ContentFiles/AdultandAdolescentGL.pdf )

[6] Centers for Disease Control and Prevention. Guidelines for Prevention and Treatment of Opportunistic Infections in HIV-Infected Adults and Adolescents. June 18, 2008; 1-134. (http://aidsinfo.nih.gov/contentfiles/Adult_OI.pdf )

[7] Panel on Antiretroviral Guidelines for Adult and Adolescents. Guidelines for the Use of Antiretroviral Agents in HIV-1-Infected Adults and Adolescents. Department of Health and Human Services. January 29, 2008; 1-128. (http://aidsinfo.nih.gov/ContentFiles/AdultandAdolescentGL.pdf )

[8] Centers for Disease Control and Prevention. Guidelines for Prevention and Treatment of Opportunistic Infections in HIV-Infected Adults and Adolescents. June 18, 2008; 1-134. (http://aidsinfo.nih.gov/contentfiles/Adult_OI.pdf )

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