Publications: A Guide to the Clinical Care of Women with HIV/AIDS, 2005 edition

 

Table 7-12: 1994 Revised Human Immunodeficiency Virus Pediatric Classification System
Immune Category <12 Mo 5 Yr <6-12 Yr
CD4/mm3 % CD4/mm3 % CD4/mm3 %
Category 1: no suppression greater than or equal to 1500 greater than or equal to 25% greater than or equal to 1000 greater than or equal to 25% greater than or equal to 500 greater than or equal to 25%
Category 2: moderate suppression 750–1499 15%–24% 500–999 15%–24% 200–499 15%–24%
Category 3: severe suppression <750 <15% <500 <15% <200 <15%
Clinical Category Children < 13 Yr
Category N: not symptomatic Children who have no signs or symptoms considered to be the result of HIV infection or who have only one of the conditions listed in category A.
Category A: mildly symptomatic

Children with 2 or more of the following conditions but none of the conditions listed in categories B and C:

  • Lymphadenopathy (greater than or equal to0.5 cm at more than two sites; bilateral = one site
  • Dermatitis
  • Hepatomegaly
  • Parotitis
  • Splenomegaly
  • Recurrent or persistent upper respiratory infection, sinusitis, or otitis media
Category B: moderately symptomatic

Children who have symptomatic conditions, other than those listed for category A or category C, that are attributed to HIV infection. Examples of conditions in clinical category B include, but are not limited to, the following:

  • Anemia (<8 gm/dL), neutropenia (<1,000/mm3), or thrombocytopenia (<100,000/mm3) persisting for greater than or equal to 30 days
  • Herpes zoster (ie, shingles) involving at least two distinct episodes or more than one dermatome
  • Bacterial meningitis, pneumonia, or sepsis (single episode)
  • Leiomyosarcoma
  • Candidiasis, oropharyngeal (ie, thrush) persisting for > 2 months in children aged > 6 months
  • Lymphoid interstitial pneumonia (LIP) or pulmonary lymphoid hyperplasia complex
  • Cardiomyopathy
  • Nephropathy
  • Cytomegalovirus infection with onset before age 1 month
  • Nocardiosis
  • Diarrhea, recurrent or chronic
  • Fever lasting > 1 month
  • Hepatitis
  • Toxoplasmosis with onset before age 1 month
  • Herpes simplex virus (HSV) stomatitis, recurrent (ie, more than two episodes within 1 year)
  • Varicella, disseminated (ie, complicated chickenpox)
  • HSV bronchitis, pneumonitis, or esophagitis with onset before age 1 month
Category C: severely symptomatic Children who have any condition listed in the 1987 surveillance case definition for acquired immunodeficiency syndrome, with the exception of LIP (which is a category B condition)
Source: Adapted from CDC, 1994.