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H H S Department of Health and Human Services
Health Resources and Services Administration
HIV/AIDS Programs

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Clinical Care Guidelines/Protocols

The U.S. Department  of Health and Human Services (HHS) issues a series of guidelines to help doctors provide care and treatment to people with living HIV in the U.S. In addition HRSA has developed complementary clinical protocols and practices that provide detailed information on the effective delivery of HIV care.

HHS Clinical Guidelines

Clinical guidelines outline the science and recommendations for treatment of HIV (for example, antiretroviral therapy, opportunistic infection treatment, and prophylaxis) as well as provide recommendation for conducting HIV testing and counseling.

These guidelines and recommendations are intended for clinicians, public health professionals, Ryan White HIV/AIDS Program recipients, program managers in clinical and non-clinical settings, people living with HIV, and the general public. 

These guidelines are frequently updated and should be accessed directly at: Clinical Guidelines for the Treatment of HIV/AIDS

Clinical Protocols and Practices

The following HIV-related protocols and clinical practices have been developed by various panels of HRSA experts and other leaders in the field of HIV care and treatment.  These guidelines are updated on an ongoing basis.

Current Editions

Guide for HIV/AIDS Clinical Care, 2014 (PDF - 6 MB)

A Guide to the Clinical Care of Women with HIV, 2013 (PDF - 6.5 MB)

A Guide for Evaluation and Treatment of Hepatitis C in Adults Coinfected with HIV, 2011 (PDF - 381 KB)

Archived Editions

A Guide to the Primary Care of People with HIV/AIDS, 2006 (PDF - 2.2 MB)

A Pocket Guide to Adult HIV/AIDS Treatment, 2006 (PDF - 1.1 MB)

A Guide to the Clinical Care of Women with HIV/AIDS, 2005 (PDF - 7.6 MB)

Health Care and HIV: Nutritional Guide for Providers and Clients, 2002 Exit Disclaimer